Does Topical Lidocaine Decrease Sweat During Exercise in the Heat?

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control.

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Key information

Conditions

Sweat Pore Closure Behavior Motor Activity

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

San Diego State University

San Diego, California, 92120-1805, United States

About this study

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control. Sweat will be collected via macroducts attached to each arm. Sweat production on each arm will be compared using t-tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18-35 years of age -

Exclusion criteria

pregnant females

Treatment and study plan

Lidocaine

Drug

effect of lidocaine on sweat production during exercise in the heat

Control

Other

one arm will be pretreated with topical lidocaine, the other arm will not

Primary outcomes

volume of sweat produced during exercise following topical lidocaine

Time frame: one hour of exercise

Volume of sweat produced during exercise following tipocal lidocaine

Sponsors and collaborators

Lead sponsor

San Diego State University

Other

Registry information

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2022
First posted: May 18, 2022
Registry last updated: Aug 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed