Skip to main content
OpenTrials
Completed

NCT Number: NCT07139340

Does the Use of HA Gel Following Third Molar Extraction Decrease the Incidence of Alveolar Osteitis?

The study aimed to investigate the effectiveness of Hyaluronic Acid gel on decreasing the incidence of alveolar osteitis after mandibular third molar extraction.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Alveolar Osteitis Dry Socket Mouth Diseases Stomatognathic Diseases

Age range

18 year–33 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Delta university for science and technology

Gamasa, Dakahlia Governorate, 7731168, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy patients (ASA=1)
  • Patients need extraction of mandibular third molar
  • Patients can attend recalls

Exclusion criteria

  • Smoking patients
  • Patients taking oral contraceptive pills
  • Bad oral hygiene

Treatment and study plan

HA gel

Other

Hyaluronic Acid gel 0.8% 1 mL

Other names: Hyaluronic Acid gel

Primary outcomes

  1. Occurence of Alveolar Osteitis (AO)

    Time frame: 7 postoperative days

    Presence of empty extraction socket without healing clot indicates AO (measured by clinical inspection; Presence of AO=1, Absence of AO=0)

Secondary outcomes

  1. Postoperative pain

    Time frame: 7 postoperative days

    Presence of postoperative pain (measured by Visual Analogue Scale (VAS) from 0 (least pain) to 10 (worst pain))

Sponsors and collaborators

Lead sponsor

Delta University for Science and Technology

Other

Collaborators

  • Mansoura University

Registry information

Important dates

Study start
2021
Primary completion
2025
Study completion
2025
First posted
Aug 24, 2025
Registry last updated
Jul 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.