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Completed

NCT Number: NCT00179595

Does the Relaxation Response Inhibit Acute Stress?

The purposes of this study are:

1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults. 2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.

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Key information

Conditions

Healthy

Age range

18 year–49 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Beth-Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States

About this study

The purposes of this study are:

  • To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
  • To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy individual
  • age:18-49 years
  • able to read and understand English
  • able to attend al study visits
  • access to a telephone (to schedule visits)

Exclusion criteria

  • current smoking
  • asthma
  • current use of any prescription or psychoactive medications or supplements
  • either:
  • no prior experience with RR eliciting techniques
  • at least 3 years of regular RR elicitation (at least 20 min/day)
  • BMI >30
  • exhaled nitric oxide levels >60 ppb
  • abnormal lab values (Hct <32,creatinine >1.3, glucose >200
  • pregnancy

Treatment and study plan

relaxation response- meditation

Behavioral

Primary outcomes

  1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.

Secondary outcomes

  1. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Sponsors and collaborators

Lead sponsor

Beth Israel Deaconess Medical Center

Other

Collaborators

  • Centers for Disease Control and Prevention

Registry information

Important dates

Study start
2002
Primary completion
2011
Study completion
2011
First posted
Sep 16, 2005
Registry last updated
Feb 16, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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