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Completed

NCT Number: NCT02708420

Does Glidescope Video Laryngoscope is Related to Less Hemodynamic Response?

Laryngoscopy and endotracheal intubation causes significant hemodynamic response and thus presents an increased risk for patients undergoing cardiac bypass surgery. Prevention or reduction of this increment is important for hemodynamic control. In this randomized single blind study, the aim of this study is to compare the hemodynamic responses of two different laryngoscopy techniques with Glidescope and Macintosh laryngoscope in coronary cardiac bypass surgery patients.

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Key information

Conditions

Blood Pressure

Age range

40 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

GATA Haydarpasa Training Hospital

Istanbul, Asia, 34668, Turkey (Türkiye)

About this study

Laryngoscopy and endotracheal intubation causes significant hemodynamic response and thus presents an increased risk for patients undergoing cardiac bypass surgery. Prevention or reduction of this increment is important for hemodynamic control. In this randomized single blind study, the aim of this study is to compare the hemodynamic responses of two different laryngoscopy techniques with Glidescope and Macintosh laryngoscope in coronary cardiac bypass surgery patients. After induction with our institutional protocol for cardiac bypass surgery, hemodynamic data including heart rate, systolic and diastolic arterial pressure data will be recorded. Time for intubation, age, sex, ASA status data will also be recorded.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologists (ASA) physical Status 2-3
  • Patients undergoing elective cardiac bypass surgery

Exclusion criteria

  • Difficult intubation history
  • Need for Rapid sequence intubation or alternative intubation method
  • Emergency procedures
  • Patients that have predictive factors for difficult intubation
  • Patients with permanent pacemaker

Treatment and study plan

Glidescope

Device

This standard GlideScope (GS) technique involves a midline laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Macintosh laryngoscope

Device

This technique involves a laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.

Primary outcomes

  1. Change in systolic blood pressure

    Time frame: 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

    invasive blood pressure (mmHg) monitoring

  2. Change in heart rate

    Time frame: 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

    Heart rate (beats per minute) will be measured before induction, and throughout and after laryngoscopy

  3. Change in diastolic blood pressure

    Time frame: 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

    invasive blood pressure (mmHg) monitoring

  4. Change in mean arterial pressure

    Time frame: 5 minutes;At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes

    invasive blood pressure (mmHg) monitoring

Secondary outcomes

  1. Procedure time

    Time frame: 10 minutes

    Total laryngoscopy and intubation time (minutes)

  2. Cormack lehane laryngoscopic view will be recorded

    Time frame: 10 minutes

    laryngoscopic view data will be recorded according to Cormack Lehane scale (A Scale with 1-4)

Sponsors and collaborators

Lead sponsor

Gata Haydarpasa Research Hospital

Other

Registry information

Official study title

Comparison of Hemodynamic Responses to Endotracheal Intubation With Glidescope Video Laryngoscope and Macintosh Direct Laryngoscope in Patients Undergoing Coronary Artery Bypass Surgery

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Mar 15, 2016
Registry last updated
Jun 14, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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