Completed

NCT Number: NCT01797328

Does Cold Provocation Increase Brown Adipose Tissue Volume?

About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Brown Adipose Tissue, Human

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Health Science, Linköping

Linköping, 58185, Sweden

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy subjects -

Exclusion criteria

any significant disease, ot other conditions that interferes with magnetic resonance imaging

Treatment and study plan

cold arm

Procedure

1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering

warm arm

Procedure

To the best of ability avoid feeling cold during 6 weeks

Primary outcomes

Brown Adipose Tissue, Absolute Volume

Time frame: Baseline and 6 week

Sub-clavicular brown adipose tissue volume by magnetic resonance imaging (liters)

Sponsors and collaborators

Lead sponsor

University Hospital, Linkoeping

Other

Registry information

Official study title

Study of the Effects of Temperature on Amount of Brown Adipose Tissue in Humans

Important dates

Study start: 2013
Primary completion: 2015
Study completion: 2015
First posted: Feb 22, 2013
Registry last updated: Apr 25, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.