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Completed

NCT Number: NCT06493617

Does Cervical Mobilization Have an Effect on Hand Function in Patients With Double Crush Syndrome?

All Double Crush Syndrome patients were assessed via VAS, BCTQ & Nerve conduction study before and after the treatment program.

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Key information

Age range

25 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Al Ryada University for Science and Technology

Sadat, Menoufia, Egypt

About this study

The patients were classified randomly into two groups, the control group received a standard physical therapy program of nerve glide, hand strengthening exercise and mobilization and the study group they received a cervical mobilization in addition to the standard physical therapy program for 12 sessions.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Thirty female patients diagnosed as Double Crush Syndrome based on the clinical diagnostic criteria of the American Academy of Neurology, (American Academy of Neurology 2019).
  • Patient ages ranged from 25 to 35 years old. Patient who reported pain, hyperesthesia, and/or paresthesia at the course of median nerve distribution and upper limb.
  • A Nerve Conduction Study (NCS) evidence of peripheral entrapment of median nerve at level of carpal bone "Carpal tunnel Syndrome" with a fractionated sensory nerve conduction velocity for the median nerve across the wrist of 40 m/s or less and with sensory peak latency > 3.6 ms and recordable and with motor distal latency >4.4 ms and less than 6.5ms.

Exclusion criteria

  • Patients had Systemic disease causes double Crush Syndrome as rheumatoid arthritis (RA), thyroid disease, Diabetes mellitus (DM), Pregnant women, Patients with concomitant neurological disease as peripheral neuropathy, Patients with history of wrist surgery, fracture, or carpal tunnel injection in the last two weeks before the study, Patients who have wasting of the thenar muscles, Patients with previous surgery for CTS.
  • Patients with complete conduction block on EDX or previous regular exposure to hand-held vibrating tools, Patients with Nerve Conduction Study with motor distal latency > 6.5 ms.

Treatment and study plan

cervical mobilization

Other

The technique is used to mobilize a specific cervical or upper thoracic segment (C2-C3 through T3-T4) in a posterior to anterior direction. The therapist gently applies pressure in an anteroposterior direction in the plane of the facet joint to assess mobility, resistance, end feel, and pain provocation. Gentle oscillations can be used to either inhibit pain (grades I and II) or restore motion (grades III and IV). Slight variations in depth and direction of force can be used to optimize the therapeutic effects of this technique.

traditional physical therapy treatment

Other

tendon gliding exercises, median nerve gliding exercise, strengthening exercises for 60 minutes

Primary outcomes

  1. Visual analogue scale

    Time frame: 4 weeks

    Used to assess degree of pain

  2. Boston carpal tunnel syndrome questionnaire

    Time frame: 4 weeks

    Used to assess patients' functional ability and symptoms severity

  3. Nerve conduction study

    Time frame: 4 weeks

    Used to assess sensory and motor fibers of median nerve to determine the improvement in nerve capacity and hand function

Sponsors and collaborators

Lead sponsor

Ahmed Alshimy

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2024
First posted
Jul 10, 2024
Registry last updated
Jul 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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