Skip to main content
OpenTrials
Completed

NCT Number: NCT04510337

Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects Depth of Blockade

This study aim is to compare the effect of magnesium sulphate combined with low dose rocuronium versus standard dose rocuronium

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Anesthesia

Age range

30 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Cancer Institute

Cairo, 11796, Egypt

About this study

Comparing the effect of magnesium sulphate combined to low dose rocuronium versus standard dose rocuronium in cancer patients undergoing direct laryngoscopy for laryngeal tumors regarding intubating conditions, intraoperative relaxation, depth of anesthesia and recovery time.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with Laryngeal tumors

ASA I-II

Age 30-70 years

Exclusion criteria

Renal and or hepatic insufficiency

Neuromuscular disease

Large glottic and/or supra-glottic lesions with or without breathing difficulties

Known allergy to any of the used drug

Treatment and study plan

standard rocuronium dose

Drug

0.6 mg/kg rocuronium during induction of anesthesia

Other names: standard dose rocuronium

Magnesium sulfate

Drug

50 mg/kg magnesium sulphate added to 0.40 mg/kg rocuronium

Other names: low dose rocuronium

Primary outcomes

  1. Onset and duration of muscle relaxant

    Time frame: 90 minutes

    Onset time of muscle relaxant and duration

Secondary outcomes

  1. Degree of muscle relaxation

    Time frame: 90 minutes

    depth of blockade

Sponsors and collaborators

Lead sponsor

National Cancer Institute, Egypt

Other

Registry information

Official study title

Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects the Depth of Blockade in Cancer Patients Undergoing Direct Laryngoscope Surgical Procedures

Important dates

Study start
2018
Primary completion
2021
Study completion
2021
First posted
Aug 12, 2020
Registry last updated
Mar 5, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.