Do Low High Density Lipoprotein (HDL) Levels Predict Treatment Outcome in Patients With Chronic Hepatitis C Viral Infection?

The working hypothesis is that the low HDL serum level predict favorable response to anti viral treatment in chronic HCV (genotype 1) viral infection. This might be used to improve the rate of sustained virologic response.

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Key information

Conditions

Chronic Hepatitis C Viral Infection

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ziv medical center liver unit

Safed, Israel, Israel

About this study

Lipoproteins are closely connected to the process of hepatitis C virus (HCV) infection. Metabolic syndrome predicts negative treatment outcome in HCV infection.

Aim: to assess the association between lipids components of the metabolic syndrome and sustained viral response (SVR).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Chronic HCV genotype 1 naive patients

Exclusion criteria

Co infection with HBV, HIV, HDV
Decompensated liver disease

Treatment and study plan

Responders

Other

Responders

Non Responders

Other

Non Responders

Primary outcomes

sustained viral response

Time frame: 72 weeks

achieving SVR

Sponsors and collaborators

Lead sponsor

Ziv Hospital

Other Gov

Collaborators

Hillel Yafe MC Hadera

Registry information

Official study title

Do Low HDL Levels Predict Treatment Outcome in Patients With Chronic Hepatitis C Viral Infection?

Important dates

Study start: 2008
Primary completion: 2008
Study completion: 2009
First posted: Jul 9, 2010
Registry last updated: Jul 9, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.