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Completed

NCT Number: NCT06489509

Distribution of Pulmonary Ventilation in Lateral Decubitus of Healthy Adults Under Non-Invasive Mechanical Ventilation

The aim was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects.

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Key information

Conditions

Noninvasive Ventilation Patient Positioning

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Attikon University Hospital, Athens, Attica, Greece

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About this study

In lateral decubitus, the largest percentage of pulmonary ventilation of non-sedated subjects is distributed mainly in the dependent lung. The aim It was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects. The volunteers were noninvasively ventilated in both lateral positions and supine positions at the beginning and end of the process. It is concluded that implementing Non-Invasive Ventilation in the lateral body position resulted in increased ventilation of the dependent lung. In contrast, the respective ventilation of the non-dependent lung was further decreased.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy Volunteers

Exclusion criteria

  • Chronic respiratory disease
  • BMI>40
  • Smoking history

Treatment and study plan

Positive End Expiratory Pressure 5 H2O

Device

Positive End Expiratory Pressure 5 H2O from CPAP apparatus

Positive End Expiratory Pressure 10 H2O

Device

Positive End Expiratory Pressure 5 H2O from CPAP apparatus

Primary outcomes

  1. The percentage change in pulmonary ventilation

    Time frame: Up to 3 minutes

    The percentage change in pulmonary ventilation was measured at each position, without applying external positive end-expiratory pressure and under positive end-expiratory pressure of 5 and 10 cmH2O

Sponsors and collaborators

Lead sponsor

Attikon Hospital

Other

Registry information

Official study title

Distribution of Pulmonary Ventilation in Lateral Decubitus of Healthy Adults Under Non-Invasive Mechanical Ventilation Supply

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jul 8, 2024
Registry last updated
Jul 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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