University Hospital, Angers
Angers, France
Location status: Recruiting
NCT Number: NCT06343844
Following myocardial infarction, female individuals demonstrate a poorer prognosis, characterized by elevated rates of mortality and heart failure. A primary hypothesis suggests unfavorable cardiac remodeling in women. This remodeling, defined as alterations in cardiac size and shape post-infarction, necessitates repeated non-invasive imaging for study.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Angers, France
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
non-invasive cardiac imaging (echocardiography and MRI)
Time frame: baseline; 3 months and 1 year after myocardial infarction onset
The primary outcome measure will be the occurrence of left ventricular remodeling (defined as a change in ventricular volume of more than 10% during follow-up) measured with cardiac imaging (echocardiography and MRI)
Time frame: 3 months
Changes in ventricular volumes between acute phase and 3 months measured with cardiac imaging (echocardiography and MRI)
Time frame: 1 year
Changes in ventricular volumes between acute phase and 1 year measured with cardiac imaging (echocardiography and MRI)
Time frame: 3 months and 1 year
renal function: uremia and creatinine levels, combined with an assessment of the protein-to-creatinine ratio in urine samples, and a cyto-bacteriological examination of urine to detect hematuria; hepatic function: The Fibroscan® is a device that enables a non-invasive and efficient assessment of liver fibrosis and steatosis within minutes at the patient's bedside, providing an immediate result displayed on the device screen; peripheral artery disease: Doppler echocardiography of the supra-aortic trunks; way of life : dietetary, stress and physical activity scores common CV risk factors: prior history of hypertension, hypercholesterolaemia, tobacco use, diabetes
Time frame: yearly, up to 10 years
Occurrence of complications and cardiovascular events (cardiovascular death, heart failure, stroke, or reinfarction)
Time frame: yearly, up to 10 years
Anxiety/Depression (A.D) score: 2 scales from 0 to 21, the greatest the more prone to either anxiety or depression
Time frame: yearly, up to 10 years
Mediteranean diet score (MED): from 0 to 14, the greatest the more relevant for mediteranean diet
Time frame: yearly, up to 10 years
physical activity: lipid research clinics (LRC); 2 scales from 1 to 5, the greatest the less active
Time frame: baseline
presence or absence of endometriosis
Time frame: baseline
presence or absence of polycystic ovary
Time frame: baseline
presence or absence of uterine fibroma
Time frame: baseline
presence or absence of hormonal therapy
Time frame: baseline
date of first period
Time frame: baseline
number of pregnancy
Time frame: baseline
number of children
Time frame: baseline
absence or presence of obstetrical events (hypertension, diabete, microsomia and macrosomia)
Time frame: baseline
absence or presence of menopause
Contact information is provided by the study sponsor or research team.
University Hospital, Angers
Other Gov
Acronym: REMOVE 2
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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