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OpenTrials
Completed

NCT Number: NCT06322823

Direct Thawing of Vitrified Human Blastocyst

There are more than million frozen embryo transfers around the world each year; a faster, safer, and cheaper method can save a significant amount of money for patients undergoing IVF treatment worldwide.

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Key information

Conditions

IVF

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

David Yiu Leung Chan

Hong Kong, 000000

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who are willing to use direct-thawed blastocysts

Exclusion criteria

  • Patients who are not willing to use direct-thawed blastocysts

Treatment and study plan

direct thawing

Procedure

Vitrified blastocysts will be thawed directly into 1ml G-TL medium

Vitrification

Procedure

Vitrified blastocysts will be thawed using commercially available one-step media.

Primary outcomes

  1. blastocysts survival rate

    Time frame: up to 6 months

    The overall survival rate for thawed blastocysts using different thawing method will be compared.

Secondary outcomes

  1. ferilization rate

    Time frame: up to 12 months

    The fertilization rate of frozen embryos using different thawing methods will be compared.

  2. pregnancy rate

    Time frame: up to 12 months

    The pregnancy rate of patients who will be scheduled for the transfer of frozen embryos using different thawing methods will be compared.

  3. live birth rate

    Time frame: up to 24 months

    The live birth rate of patients who will be scheduled for the transfer of frozen embryos using different thawing methods will be compared.

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Registry information

Official study title

A Pilot Study on Developing a One-step Direct Thawing Method on Human Blastocysts With Transcriptomic and Methylomic Comparison to Conventional Vitrified-thawing Method

Important dates

Study start
2020
Primary completion
2022
Study completion
2023
First posted
Mar 21, 2024
Registry last updated
Mar 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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