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Completed

NCT Number: NCT03028727

Diode Laser Therapy As An Adjunct To Scaling And Root Planing

Laser therapy has been proposed as a novel treatment option in controlling subgingival microorganisms. This randomized controlled clinical trial evaluates the effect of 980nm diode laser as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis (CP).

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Key information

About this study

Conventional mechanical debridement can achieve a temporary decrease in the subgingival levels of Pg along with other pathogens. However, mechanical therapy alone may fail to eliminate pathogenic bacterial niches in inaccessible areas like deep pockets, root concavities, furcation areas etc. In search of more efficient and less traumatic techniques to improve periodontal healing, researchers proposed the use of lasers in periodontal therapy.

The adjunctive use of lasers with conventional tools may facilitate treatment and have the potential to improve healing. The diode laser is highly absorbed in hemoglobin and other pigments and is excellent for use in soft tissue surgical procedures.Laser application in improving clinical outcome in periodontal therapy, needs to be further investigated with well designed clinical trials. The investigators attempted to evaluate the efficacy of diode laser as an adjunct to SRP in the management of CP by evaluating clinical parameters coupled with quantitative estimation of P.gingivalis using Real-time Polymerase chain reaction (RT-PCR) assay.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 40 systemically healthy subjects diagnosed with generalized moderate CP in the age group of 30 to 50 years.
  • Minimum of 20 teeth having atleast two non-adjacent sites per quadrant with probing pocket depth of ≥ 5mm and clinical attachment loss of 3- 4 mm

Exclusion criteria

  • Patients who had undergone periodontal therapy 6 months prior to the commencement of the study.
  • Subjects on antibiotics or immunosuppressants.
  • Chronic smokers, alcoholics, smokeless tobacco users.
  • Subjects with acute illnesses/acute intraoral lesions.
  • Pregnant women
  • Subjects who had undergone extensive restorative dental treatment.

Treatment and study plan

Ultrasonic Scaling and root planing

Procedure

Procedure of scaling and root planing at day 0 and at 1 week

980 nm diode laser irradiation

Procedure

Procedure of scaling and root planing and application of 980 nm diode laser at day 0 and at 1 week

Primary outcomes

  1. Change in levels of P.gingivalis

    Time frame: 14 weeks

    Microbial profile was assessed using PCR at baseline, 4-6 weeks and 12-14 weeks post treatment in both the study groups.

Secondary outcomes

  1. Change in gingival index

    Time frame: 14 weeks

    Gingival index by Loe and Silness was assessed at baseline, 4-6 weeks and 12-14 weeks post treatment in both the groups

  2. Change in plaque index

    Time frame: 14 weeks

    Plaque index by Silness and Loe was assessed at baseline, 4-6 weeks and 12-14 weeks

  3. Change in probing pocket depth

    Time frame: 14 weeks

    Probing pocket depth was assessed at baseline, 4-6 weeks and 12-14 weeks

  4. Change in clinical attachment level

    Time frame: 14 weeks

    Clinical attachment level was assessed at baseline, 4-6 weeks and 12-14 weeks

Sponsors and collaborators

Lead sponsor

KLE Society's Institute of Dental Sciences

Other

Registry information

Official study title

Diode Laser Therapy As An Adjunct To Non-Surgical Management Of Chronic Periodontitis - A Pilot Study

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Jan 23, 2017
Registry last updated
Jan 23, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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