Linda Evertsson
Stockholm, 11883, Sweden
NCT Number: NCT05337917
Case control study, investigating what hand function and sensory function do patients perform 3-10 years following digital nerve injury and repair. The aim is to investigate if hand function is more limited following digital nerve injury in the thumb, index- and little finger, compared to less unburdened sensory surfaces in the fingers. Secondary aim is to investigate the long term sensory function following digital nerve injury.
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Notify Me18 year–100 year
All sexes
Observational
Stockholm, 11883, Sweden
Eligible patients are individuals treated at the Department of Hand surgery in Stockholm, Sweden during 2012-2018. Inclusion criteria include diagnostic codes (ICD-10) for a digital nerve injury in the thumb (S64.3) or finger (S64.4) in combination with the surgical code (KKÅ97) Nomesco classification of surgical procedures for nerve repair (ACB29). Exclusion criteria are concomitant flexor tendon injury and/or skeletal injury, amputations, and severe soft tissue injuries. Patients residing outside the Stockholm region and children below 18 years of age are also excluded. Initially a total number of 1330 patients have been identified. All medical records have been thoroughly scrutinized. After excluding concomitant tendon injury, a total of 606 patients remained with isolated digital nerve injury. A randomly selected sample of participants have been assigned to two groups: Patients with an injury to the digital nerve of the thumb, digit II radial side, digit V ulnar side were assigned to the "case" group and matched "controls" were randomly selected among patients with an injury to the digital nerves of either the ulnar side of digit II, either nerve of digit III and digit IV or the radial nerve of digit V. Cases and controls have been matched according to sex, year of injury and patient age.
For the purpose of this study, a clinical evaluation to investigate hand function, sensory function, strength, and ability to discriminate warm and cold and sharp and dull will be conducted. Questionnaires are used for Patient Reported Outcome Measures (PROM): Disability of the Arm Shoulder, and Hand (QuickDASH), Patient questionnaire HQ8 arm and hand (HQ8), The Hospital Anxiety and Depression Scale (HADS), Saltin-Grimby Physical Activity Level Scale (SGPALS), and in addition Douleur Neuropathique en 4 Questions (DN4) for assessment of neuropathic pain will be performed. All outcomes will be compared between groups defined as case (digital injury to the thumb, radial nerve of the index finger or ulnar nerve of the little finger) or control (all other digital nerve injuries).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
All patients (cases and controls) were subject to surgical repair of digital nerve injury.
Time frame: 3-10 years post operatively
Measured by Mini Sollerman test for handfunction.
Time frame: 3-10 years post operatively
Semmes Weinstein, Static two point discrimination
Time frame: 3-10 years post operatively
Static two point discrimination
Time frame: 3-10 yrs post op
QuickDASH (Disability of the Arm Shoulder and Hand)
Time frame: 3-10 yrs post op
HQ8 (HAKIR Questionnaire 8 questions)
Time frame: 3-10 yrs post op
SGPALS (Saltin-Grimby Physical Activity Level Scale)
Time frame: 3-10 yrs post op
DN4 (Douleur neuropathique 4 levels)
Time frame: 3-10 yrs post op
HADS (Hospital Anxiety and Depression Scale)
Time frame: 3-10 yrs post op
Physical activity scale.
Time frame: 3-10 yrs post op
Goniometer measurements of finger joints
Time frame: 3-10 yrs post op
Grip strength as measured by Pinch gauge
Time frame: 3-10 yrs post op
Grip strength as measured by JAMAR
Karolinska Institutet
Other
Long-term Hand Function and Sensation Following Digital Nerve Injury and Repair- a Case Control Study.
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