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Completed

NCT Number: NCT01917045

Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia

The investigators noticed that Body Fat Ratio might have great influence on the efficacy of different lipid soluble anesthetics. The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.

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Key information

Conditions

Post Operative Pain Management

Age range

20 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologists grade I-II
  • adults aged over 20 and below 50 years old,
  • non-smoker,
  • with normal hepatic and renal function.

Exclusion criteria

  • smoker ,
  • any kind of mental disorder or
  • history use of analgesics for more than 10 consecutive days,
  • asthma; and
  • those with digestion tract disorder who would get nausea or vomiting much more easily than normal people.

Treatment and study plan

Sufentanil (R30730, brand name Sufenta)

Drug

sufentanil 1ug/ml

Sufentanil (R30730, brand name Sufenta) + Morphine

Drug

sufentanil 0.5ug/ml+morphine 0.25mg/ml

Morphine

Drug

morphine 0. 5mg/ml

Primary outcomes

  1. visual analogue pain scores

    Time frame: 24hour

    we evaluate visual analogue pain scores at different time points within 24 hours after surgery

Secondary outcomes

  1. nausea & vomiting

    Time frame: 24hour

    we evaluate nausea & vomiting at different time points within 24 hours after surgery. we ask the patient if she feel nausea or/and occured vomit, if so, 1 time will be recorded in the time point for incidence.

Sponsors and collaborators

Lead sponsor

Peking University First Hospital

Other

Registry information

Official study title

Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia --- a Double Blind Randomized Study

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Aug 6, 2013
Registry last updated
Aug 6, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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