Assiut University Hospital
Asyut, Egypt
NCT Number: NCT07702188
* Identification of the most effective approach for different lesion types * Correlation between approach and complication rates
Trial opening soon.
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Interventional
Not applicable
Asyut, Egypt
The sphenoid sinus is one of the most anatomically complex and surgically challenging paranasal sinuses due to its deep location ,wide anatomical variation and proximity to critical neurovascular structures.
Important structures are adjacent to the sphenoid sinus include the dura, pituitary, optic nerve, cavernous sinus, pterygoid canal and nerve, internal carotid artery, and cranial nerves III, IV, VI, V1, V2, which are vulnerable to injury with sphenoid disease.
Wide anatomical variation such as Degree of Pneumatization , Septation Patterns , Sinus Size and Shape, Ostium Location ,Onodi Cells, Prominence or dehiscence of nearby structures.
Therefore, surgeons must carefully select the extent of dissection to create a sphenoid opening that matches the patient's pathology while avoiding the risks associated with overly extensive openings and drilling, which may prolong healing and increase the likelihood of scarring and stenosis.
Diagnostic nasal endoscopy procedures and imaging techniques are of great value for an early and precise diagnosis.
Moreover, endoscopic sinus surgery is a safe and effective technique that allows a direct route to the sphenoid sinus.
Because of its close vicinity to important and vulnerable structures of the skull base, delay in diagnosis and treatment can be potentially lethal.
Sphenoid sinus lesions may range from mild, isolated inflammation to erosive tumors with cranial nerve deficits or cases requiring access to a pneumatized lateral recess .
Additionally, conditions such as tumors, encephaloceles, mucoceles, and skull base lesions demand extra preoperative planning and careful technique selection.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Different approaches include:
type I, sphenoid ostial dilation. type IIa, transnasal sphenoidotomy (sphenoidotomy without ethmoidectomy). type IIb, transethmoidal sphenoidotomy (sphenoidotomy with ethmoidectomy). type III, bilateral, common cavity sphenoidotomy, or "sphenoid drill-out;" type IV, transpterygoid approach, to expose the lateral sphenoid sinus recess. type V, sphenoid nasalization, completely removing the sphenoid sinus floor.
Time frame: 6 months
Time frame: 6 month
complications rate (csf leakage , optic nerve injury, carotid artery injury)
Contact information is provided by the study sponsor or research team.
Ahmed elrahman mohamed azzam, lecturer
CONTACT
Doaa Araby Mohamed, assistant lecturer
CONTACT
Assiut University
Other
Different Approaches for Sphenoid Sinus
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