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Completed

NCT Number: NCT01488032

Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

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Key information

Conditions

Normal Tension Glaucoma Eye Diseases Glaucoma High Tension Glaucoma Low Tension Glaucoma Ocular Hypertension Optic Nerve Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

About this study

It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • persons over 18 years
  • men or women
  • with normal- and high-tension glaucoma

Exclusion criteria

  • cataract
  • cloudy cornea and other conditions with bad visualisation quality of optic nerve head
  • optic nerve atrophy except glaucomatous

Treatment and study plan

Primary outcomes

  1. RNFL in different segments

    Time frame: up to 9 Months

    RNFL in upper, lower, temporal and nasal segments

Sponsors and collaborators

Lead sponsor

Technische Universität Dresden

Other

Registry information

Official study title

Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma With Similar Structural Optic Nerve Damage

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Dec 8, 2011
Registry last updated
Dec 9, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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