St Michael's Hospital
Toronto, Ontario, M5B 1X2, Canada
NCT Number: NCT03218189
The World Health Organization (WHO) has developed a model list of more than 400 medicines and recommends that each country adapt the list to its own circumstances. More than 100 countries have developed essential medicines lists.
Some countries have essential medicines lists that are very similar to the WHO's model list and other countries have lists that are very different from the WHO's model list. Differences between the WHO list and country lists could be explained by features of the country including population demographics, disease prevalence, Gross Domestic Product (GDP), and healthcare system organization. Other factors such as the influence of particular individuals or organizations may also explain differences between countries.
The purpose of this project is to compare the essential medicines lists developed by countries with the WHO's model list and to identify attributes of countries that are associated with differences from the WHO list. Predictors such as region, population, life expectancy, infant mortality rate, GDP per capita, health expenditure per capita, inequality, and the corruption perception index will be considered.
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Observational
Toronto, Ontario, M5B 1X2, Canada
Statistical analysis plan for objective 3 (relationship between the total number of differences and country features)
Plots will be generated to show the relationships between variables. Correlation coefficients will be calculated where appropriate. Two separate multivariate models will be fit to the data for outcomes 2a and 2b [continuous, between 1 and 500]. A similar model will be fit the total number of differences. The analytical method will be determined by the data and may be liner regression.
Predictors:
Region-Categorical (6)
Population-Continuous
Life expectancy-Continuous
Infant mortality rate-Continuous
GDP per capita-Continuous
Health expenditure per capita
Inequality-Continuous
Corruption Perception Index-Continuous
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Observational study of country characteristics
Time frame: 1 year
The total number of differences between the WHO model list of essential medicines and the essential medicines list in each country is comprised of:
Time frame: 1 year
Time frame: 1 year
Unity Health Toronto
Other
Differences Between Essential Medicines Lists in 135 Countries and the World Health Organization's Model List of Essential Medicines
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.