Skip to main content
OpenTrials
Completed

NCT Number: NCT02435017

Dietary Phosphate and Serum Phosphorus

Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function. Substudies will be performed to review the association of nutrients and overall dietary intake compared to biomarkers available in NHANES during this period.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Phosphorus Metabolism Disorders Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Metabolic Diseases Nutritional and Metabolic Diseases Urogenital Diseases Urologic Diseases

Age range

20 year–85 year

Sex eligibility

All sexes

Study type

Observational

About this study

Data from NHANES 2003-2006 were used to evaluate the relationship between estimated dietary phosphorus intake and the measured serum phosphorus. The following variables were used:

  • Demographics: Age, sex, race/ethnicity
  • Dietary variables: Foods, food groups (as reported by the United States Department of Agriculture (USDA) method, further standardized to the Academy of Nutrition and Dietetics method for portion size and then divided into groups having inorganic phosphate additives or no inorganic phosphate additives), food weight (g), phosphorus (mg), dietary supplements
  • Socioeconomic variables: education, family income
  • Laboratory variables: serum creatinine, phosphorus; urine albumin, creatinine
  • Clinical assessments: hypertension (proportion having blood pressure ≥140 millimeters of mercury (mmHg) diastolic or ≥90 mmHg systolic or taking antihypertensive medications); hyperglycemia (proportion having serum glucose >126 mg/dL or taking medications for diabetes); kidney function based on Chronic Kidney Disease Epidemiology Collaboration (2009) equation, evaluated in 15 milliliters/min/1.73m2 increments from <15 to >105; anthropometrics (BMI, kg/m2; obesity class I, II, III)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Serum creatinine

Exclusion criteria

  • Pregnancy
  • No dietary intake interview
  • Dietary intake interview not valid
  • Answered the question "Have you had dialysis in the past year?" as "Yes"

Treatment and study plan

Primary outcomes

  1. Serum phosphorus concentration

    Time frame: approximately 24 hours

    Serum phosphorus concentration on the day that 24-hour dietary recall was obtained (reflecting dietary intake the day prior to blood draw); measured in mg/dL

Secondary outcomes

  1. Kidney function level

    Time frame: Baseline

    Kidney function estimated from Chronic Kidney Disease Epidemiology Collaboration (2009) equation, mL/min/1.73m2, and separated into 15mL/min increments

Sponsors and collaborators

Lead sponsor

Linda W. Moore

Other

Collaborators

  • The Methodist Hospital Research Institute

Registry information

Official study title

Nutrition Risk Screening in Chronic Kidney Disease (CKD) From the National Health and Nutrition Examination Survey

Important dates

Study start
2003
Primary completion
2006
Study completion
2009
First posted
May 6, 2015
Registry last updated
Sep 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.