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Completed

NCT Number: NCT02162927

Dietary Nitrate Supplementation and Crossfit Athletes

In the past, dietary nitrate supplementation has been shown to have clinical benefits in the treatment of cardiovascular issues. More recently, however, the focus of nitrate supplementation has shifted to focus of human performance, and has shown to increase the time to exhaustion during maximal intensity exercise and lower the cost of oxygen consumption during submaximal intensity exercise. Acutely, nitrate supplementation in the form of beetroot juice has been shown to increase strength measurements, as well as increase the time to complete a 2000 meter rowing ergometer test. However, to the author's knowledge, there are no studies that link the relationship between multi-day nitrate supplementation and the rowing test or the nitrate's effect on strength when in the salt form. Additionally, to the author's knowledge, no evidence has been published which relates dietary nitrate supplementation and its effects on a CrossFit circuit workout.

Our central hypothesis is that six days of dietary nitrate supplementation will improve strength, endurance, a power more than a placebo in male CrossFit athletes.

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Key information

Conditions

Age range

20 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

CrossFit Blackbox, Tallahassee, Florida, United States

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About this study

The purpose of this randomized, double-blind, crossover study is to identify if dietary nitrate supplementation improves strength , endurance, and power measurements in male CrossFit athletes. Specifically, the strength measurements will be taken using isometric and isokinetic tests on the Biodex dynamometer. Endurance will be measured using time trials for a 2000 meter rowing test and the "Fran" CrossFit workout. Finally, power will be analyzed using the Wingate cycle test.

The treatment group will receive 1 serving of f potassium nitrate KNO3- (N) (8 mmols NO3-). The placebo group will receive 1 serving of the nitrate-free placebo (PL) potassium chloride (8 mmol KCl).

The participants will complete two three-day baseline testing, with a six-day supplementation period following each round of baseline testing. Following the first six-day supplementation period, there will be a 10 day washout period before the second baseline testing begins.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • College-aged male CrossFit between the ages of 20 and 35 years (yr), a peak maximum oxygen uptake (VO2peak) of at least 50 ml/kg/min will be recruited to participate in this study.

Exclusion criteria

  • Having any thyroid and/or kidney diseases that could affect NO synthesis and/or metabolism, any illness, smoking, taking other medications, injured, not well-trained (as noted by the VO2peak), consuming any other supplements at the time of the study except protein or multivitamin, allergic to any component of the supplement, including tree nuts, in case of potential packaging mixing and contamination. Women and children as well are excluded.

Treatment and study plan

Dietary nitrate

Dietary Supplement

This pill must be taken on an empty stomach (2-3 hours after eating) and must be taken about 2-3 hours before exercise.

Potassium Chloride (placebo)

Dietary Supplement

This pill must be taken on an empty stomach (2-3 hours after eating) and must be taken about 2-3 hours before exercise.

Primary outcomes

  1. Muscular Strength

    Time frame: During 1 month of study

    Muscular Strength will be tested using the isometric and isokinetic strength tests.

  2. Muscular Endurance

    Time frame: 1 month

    Endurance will be tested using the 2000 meter rowing ergometer test and CrossFit circuit known as "Fran".

  3. Muscular Power

    Time frame: 1 month

    Power will be measured using the Wingate cycle test.

Sponsors and collaborators

Lead sponsor

Florida State University

Other

Registry information

Official study title

The Effects of Six-day Dietary Nitrate Supplementation on Strength and Endurance Measurements in Male CrossFit Athletes

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Jun 13, 2014
Registry last updated
Mar 4, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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