Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India

Severe tuberculosis (TB) leads to wasting and anorexia, increasing risk of the refeeding syndrome (RFS) as defined by current criteria. TB patients have high metabolic rates and require a high calorie diet, with nutritional supplementation programs improving outcomes. BMI inversely correlates with mortality in these patients. Risk of RFS, a life-threatening syndrome associated with initiation of feeding after a period of low intake, has not been studied in this population and it is not known whether severely malnourished TB patients benefit from lower caloric intake. This study aimed to examine the prevalence of RFS in TB inpatients in rural India and correlate this with baseline and inpatient caloric intake.

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Key information

Conditions

Tuberculosis Actinomycetales Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections Malnutrition Mycobacterium Infections Nutrition Disorders Nutritional and Metabolic Diseases Refeeding Syndrome Severe Malnutrition

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Jan Swasthya Sahyog

Ganiyari, Chhattisgarh, India

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all adult inpatients admitted to the TB ward
able to take enteral intake

Exclusion criteria

unable to take enteral intake

Treatment and study plan

Primary outcomes

Inpatient caloric intake

Time frame: from date of admission to discharge, up to 100 weeks

Secondary outcomes

Incidence of refeeding syndrome

Time frame: from date of admission to discharge, up to 100 weeks

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Registry information

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2018
First posted: May 25, 2018
Registry last updated: May 25, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed