Skip to main content
OpenTrials
Completed

NCT Number: NCT00463255

Diet and the Aging Brain

We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Cognition Disorders Cognitive Dysfunction Mental Disorders Neurocognitive Disorders

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

University Hospital Muenster, Department of Neurology

Münster, North Rhine-Westphalia, 48149, Germany

About this study

The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects.

Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects
  • 50-80 years old
  • moderate to heavy weight
  • must be able to change diet at home

Exclusion criteria

  • diabetes
  • younger than 50 years
  • BMI < 23
  • already participating in other studys
  • MMSE > 26
  • eating disorders

Treatment and study plan

Diet

Behavioral

Primary outcomes

  1. implicit visual-motor learning of a finger sequence of the hand.

Secondary outcomes

  1. implicit learning of an artificial language

  2. several plasma levels related to cognitive functions

Sponsors and collaborators

Lead sponsor

University Hospital Muenster

Other

Registry information

Official study title

Phase IV Interventional Study: Effect of Diet on Brain Function in Elderly Healthy People

Important dates

Study start
2006
Study completion
2008
First posted
Apr 20, 2007
Registry last updated
Nov 8, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.