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OpenTrials
Completed

NCT Number: NCT02069314

Diet and Muscle Function In Older Adults

This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adults.

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Key information

Conditions

Sarcopenia Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Purdue University

West Lafayette, Indiana, 47907, United States

About this study

This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adult

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 65 years and older

Exclusion criteria

  • Diabetic
  • Acute symptoms of cardiovascular disease or congestive heart failure
  • uncontrolled hypertension
  • supplemental oxygen consumption at rest or during exercise
  • lactose intolerance
  • inability to ride a stationary cycle

Treatment and study plan

Whey protein supplementation

Dietary Supplement

subjects are asked to consume a smoothie with whey protein added

Carbohydrate (polycose) supplementation

Dietary Supplement

Subjects are asked to consume a beverage with polycose added

Primary outcomes

  1. Dietary protein effects on muscle energy use

    Time frame: participants will be measured over an average of 26 days

    gross mechanical efficiency of muscle, consuming high and low protein supplements

Secondary outcomes

  1. Effect of protein supplements on food intake

    Time frame: participants will be measured over an average of 26 days

    effects of high protein or high carbohydrate supplements on overall energy consumption in older adults.

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Registry information

Acronym: S32

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Feb 24, 2014
Registry last updated
Feb 24, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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