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OpenTrials
Completed

NCT Number: NCT03480828

Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mongi Slim Hospital

La Marsa, Tunis Governorate, 2046, Tunisia

About this study

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation.

Our study compared the utility of DTF and DE to predict extubation success.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation
  • patients without history of neuromuscular disease, or severe chronic respiratory failure

Exclusion criteria

  • patients who needed reintubation for upper airway obstruction or neurological or hemodynamic instability

Treatment and study plan

comparaison between DE and DTF in prediction of extubation success

Diagnostic Test

diaphragm ultrasound and measurement of DE and DTF in patients meeting all extubation criteria during spontaneous breathing trial

Primary outcomes

  1. extubation success

    Time frame: 48 hours after extubation

    comparaison between DE and DTF values in successfully extubated patients

Sponsors and collaborators

Lead sponsor

Mongi Slim Hospital

Other

Registry information

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Mar 29, 2018
Registry last updated
Mar 30, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.