Diagnostic Value of Fecal Calprotectin in Disorders of the Upper Gastrointestinal Tract

Fecal calprotectin is a very sensitive non-invasive inflammation marker in the detection of inflammatory bowel disease and, to a lesser degree, has also proven to be useful in adenomatous polyps, neoplasias, and infectious gastroenteritis. Elevated calprotectin levels can also be found in patients with lesion only in the upper gastrointestinal tract. However, the diagnostic value of calprotectin has never been tested in this setting. The aim of the study is therefore to determine the diagnostic value of fecal calprotectin in patients with diseases of the upper gastrointestinal tract.

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Key information

Conditions

Peptic Esophagitis Colonic Diseases Colonic Diseases, Functional Digestive System Diseases Duodenal Diseases Esophageal Diseases Esophagitis Esophagitis, Peptic Functional Dyspepsia Gastroenteritis Gastrointestinal Diseases Inflammatory Bowel Diseases Intestinal Diseases Irritable Bowel Syndrome Peptic Ulcer Stomach Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Gastroenterology & Hepatology

Basel, Basel-Stand, 4031, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients referred for upper gastrointestinal endoscopy for any reason
Older than 18 years

Exclusion criteria

Patients who are not able to provide informed consent
Patients who are not able to provide a stool sample

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Official study title

Value of Fecal Calprotectin in Upper Gastrointestinal Disease

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Jun 15, 2009
Registry last updated: Jan 12, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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