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OpenTrials
Active, Not Recruiting

NCT Number: NCT06630988

Diagnostic and Management of Hand Infection.

Primary or secondary (post-traumatic infections, notably related to bites, wounds, etc.) infections of the hand are very common situations, even if the epidemiology is poorly understood. For example, hand bite injuries represent 1.2 million referrals to the healthcare system per year in the United States. Their nosological framework extends from simple infections of the skin and soft tissues such as whitlows, to potentially severe deep damage such as arthritis and osteitis, or phlegmons of the tendon sheaths. The diagnostic approach is not consensual, and the contribution of additional biological parameters (inflammatory syndrome) and morphological investigations (x-rays, ultrasound, CT-scan or MRI) is not codified. Microbiology seems dominated by Staphylococcus aureus, but few studies have precisely described the microbial etiology. Consequently, probabilistic antibiotic therapy and the need to take bacteriological samples for secondary adaptation are not standardized. Likewise, surgical strategies (abstention, systematic washing or depending on evolution) remain operator dependent. We consequently aim to described diagnostic, management and related outcomes or hand infections in a specialized tertiary care center.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

HCL - Hôpital Edouard Herriot

Lyon, 69003, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all patient ≥ 18
  • yo followed-up for a hand infection in our tertiary care center
  • from 01/01/2014 to 31/12/2023, including
  • whitlows
  • tendinous infections
  • septic arthritis

Exclusion criteria

  • osteomyelitis

Treatment and study plan

Failure rates

Other

Describe the management failure rate for hand infections, including panariasis, phlegmons and arthritis.

Primary outcomes

  1. Percentage of treatment failure during the management of hand infections.

    Time frame: between 01/01/2014 and 31/12/2023.

    Treatment failure will be defined as infection persistence or relapse, need of unplanned surgery for septic reason or infection-related death.

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Diagnostic and Management of Hand Infection: a Retrospective Cohort in a Tertiary Care Center.

Acronym: HandInf

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Oct 8, 2024
Registry last updated
Oct 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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