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OpenTrials
Completed

NCT Number: NCT07011030

Diagnosis of Sarcopenia in Older Adults

Sarcopenia is defined as the loss of muscle strength and mass associated with aging and is one of the main causes of frailty in older people, and therefore of their ability to age gracefully. Given the aging of the French population, the diagnosis and management of this condition is a major public health issue and, in this context, it is therefore necessary to be able to quickly assess people's skeletal muscle mass.

In its recommendations, French National Authority for Health recommends the use osteodensitometry and bioimpedance analysis (BIA) to assess skeletal muscle mass in the limbs for the purpose of diagnosing sarcopenia. Traditionally, BIA assessment is performed while lying down using adhesive electrodes placed on the hands and feet. The Biody XpertZM3 is a BIA device that allows seated measurement using integrated electrodes, enabling skeletal muscle mass to be assessed by bioimpedance analysis without the use of adhesive electrodes. However, the measurement position could alter the impedances measured and therefore the results obtained compared to other devices on the market as well as osteodensitometer

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Nice

Nice, Alpes-Maritimes, 06000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men or women aged 60 or over already receiving care at the Day Hospital of the Rehabilitation, Independence and Aging Center or the Frailty Platform of the Rehabilitation, Independence and Aging Center.
  • Patients affiliated with or covered by a social security system.
  • Patients who have signed an informed consent form in advance.

Exclusion criteria

  • Vulnerable persons as defined in Articles L1121-5 to -8
  • People with pacemakers, implantable defibrillators, or other electronic medical devices
  • Musculoskeletal disorders that prevent bioimpedance measurement in a seated position
  • Any condition of fluid retention or dehydration
  • Absence of a measurement site (muscle resection or amputation)

Treatment and study plan

Measure of skeletal muscle mass

Other

Bioimpedance analysis with integrated electrodes and osteodensitometry examination

Primary outcomes

  1. Appendicular skeletal muscle mass

    Time frame: day 0

    Comparison of skeletal muscle mass of the limbs (in kg) obtained by bioimpedance analysis using integrated electrodes and using osteodensitometry

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Comparison of the Use of a Bioimpedance Meter With Integretaed Electrodes and Osteodensitometry for the Diagnosis os Sarcopenia in the Elderly

Acronym: SARCO-BIODY

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 8, 2025
Registry last updated
Dec 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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