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OpenTrials
Completed

NCT Number: NCT03023241

Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.

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Key information

Conditions

Bladder Pain Syndrome Cystitis Cystitis, Interstitial Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Interstitial Cystitis Lower Urinary Tract Symptoms Male Urogenital Diseases Overactive Bladder Pathological Conditions, Signs and Symptoms Signs and Symptoms Urinary Bladder Diseases Urinary Bladder, Overactive Urogenital Diseases Urologic Diseases Urological Manifestations

Age range

18 year–90 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cantonal Hospital Frauenfeld

Frauenfeld, Thurgau, 8501, Switzerland

About this study

Collection and analyses of bladder biopsies, bladder washings, blood and urine samples of patients with bladder pain syndrome/interstitial cystitis (BPS/IC), overactive bladder syndrome (OAB) and bladder-healthy controls. Analyses include ELISA, RT-qPCR, DNA sequencing, and immunohistochemistry techniques. Differences between patient groups are statistically evaluated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient with diagnosed BPS/IC, OAB or healthy controls
  • included healthy controls must have another pelvic surgery planned (e.g. hysterectomy)
  • being able to act and judge

Exclusion criteria

  • unstable endocrinological situation
  • severe illness

Treatment and study plan

Biopsy

Procedure

cold cup bladder biopsies and bladder washings under anesthesia, blood and urine collection

Primary outcomes

  1. Identification of new diagnostic markers for BPS/IC

    Time frame: 2 days

Secondary outcomes

  1. Identification of molecular details that lead to BPS/IC (pathogenesis).

    Time frame: 2 days

Sponsors and collaborators

Lead sponsor

Cantonal Hospital, Frauenfeld

Other

Registry information

Important dates

Study start
2004
Primary completion
2020
Study completion
2021
First posted
Jan 18, 2017
Registry last updated
Mar 31, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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