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Completed

NCT Number: NCT02316236

Dexmedetomidine to Improve Outcomes During Emergence From Retroperitoneal Laparoscopic Surgery

The study is to observe whether dexmedetomidine could reduce agitation during emergence from general anesthesia in patients undergoing retroperitoneal laparoscopic surgery.

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Key information

Conditions

Anesthesia

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Xijing Hospital

Xi'an, Shaanxi, 710032, China

About this study

Agitation during emergence is frequent after retroperitoneal urologic surgery. Dexmedetomidine is alpha-2 receptor agonist which shows sedative and algesic effect. In this study we will compare the effect of dexmedetomidine given by different protocols on emergence agitation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for retroperitoneal laparoscopic surgery
  • Patients with written informed consent

Exclusion criteria

  • Patients with difficulty of communication
  • Patients with risk of obstructive sleeping apnea syndrome

Treatment and study plan

Dexmedetomidine

Drug

an alpha-2 receptor agonist

Other names: dex

loading dose

Other

0.8ug/kg of dexmedetomidine is given in 10 minutes

Other names: LD

sustaining dose

Other

0.4ug/kg/min of dexmedetomidine is given

Other names: SD

Primary outcomes

  1. Richmond Score

    Time frame: From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour

Secondary outcomes

  1. Cough score

    Time frame: From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour

  2. Time to awake

    Time frame: From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour

    time to open eyes to verbal command

Sponsors and collaborators

Lead sponsor

Air Force Military Medical University, China

Other

Registry information

Official study title

Effect of Dexmedetomidine on Outcomes During Emergence From Retroperitoneal Laparoscopic Surgery

Acronym: DEALS

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Dec 12, 2014
Registry last updated
May 26, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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