Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy

Recurrent laryngeal nerve dysfunction and hypoparathyroidism are well-recognized important complications of thyroid surgery. The duration of convalescence, after non complicated thyroid operation, may depend on several factors of which pain and fatigue are the most important. Nausea and vomiting occur mainly on the day of operation. Glucocorticoids are well known for their analgesic, anti-inflammatory, immune modulating and antiemetic effects. The investigators therefore undertook the present study to investigate whether preoperative dexamethasone could improve surgical outcome in patients undergoing thyroid surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Benign Neoplasm of Thyroid Gland Endocrine Gland Neoplasms Endocrine System Diseases Head and Neck Neoplasms Malignant Neoplasm of Thyroid Neoplasms Neoplasms by Site Thyroid Diseases Thyroid Neoplasms

Age range

Up to 75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

ospedale San Salvatore-Reparto di Chirurgia Generale Universitaria

L’Aquila, AQ, 67100, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients undergoing thyroid surgery

Exclusion criteria

ASA physical class III or IV
age > 75 years
pregnancy

Sponsors and collaborators

Lead sponsor

Università degli Studi dell'Aquila

Other

Registry information

Official study title

Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy (and Not Only) After Thyroid Surgery. A Randomized Double-blind Placebo-controlled Trial.

Important dates

Study start: 2008
Primary completion: 2012
Study completion: 2012
First posted: Sep 24, 2012
Registry last updated: Sep 26, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed