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OpenTrials
Completed

NCT Number: NCT00802009

Dexamethasone and Analgesic Duration After Supraclavicular Brachial Plexus Blockade

Patients undergoing surgery of the hand often are treated with a nerve block in the shoulder/neck area that provides anesthesia/numbing during surgery. Nerve blocks usually last for a few hours after surgery and provide pain relief for this period. It may be possible to extend the duration of anesthesia by using a steroid, which has anti-inflammtory properties. This study will compare the duration of the nerve block when dexamethasone (steroid) is added to the anesthetic injected around the nerve.

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Key information

Conditions

Anesthesia

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Toronto Western Hospital, University Health Network

Toronto, Ontario, M6G 2N6, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients having unilateral hand or forearm surgery under Supraclavicular brachial plexus blockade.
  • ASA I-III
  • Age 18-60
  • BMI < 35

Exclusion criteria

  • Patients with a known history of hypersensitivity to local anesthetics and dexamethasone.
  • Contra-indication to regional anesthesia/ supraclavicular brachial plexus blockade e.g. bleeding diathesis, coagulopathy.
  • Peripheral neuropathy.
  • Peptic ulcer disease.
  • Diabetes Mellitus.
  • Inability to give informed consent.

Treatment and study plan

Dexamethasone

Drug

Dexamethasone 8 milligrams (liquid) will be added to standard anesthetic solution administered during routine brachial plexus nerve blockade.

Mepivicaine

Drug

Standard anesthetic solution administered during routine brachial plexus nerve blockade.

Primary outcomes

  1. Duration of anesthesia

    Time frame: hourly for first 24 hours; daily until discharge

Secondary outcomes

  1. Requirements for pain medications; complications

    Time frame: up to 3 months

Sponsors and collaborators

Lead sponsor

University Health Network, Toronto

Other

Registry information

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Dec 4, 2008
Registry last updated
Jan 26, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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