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Completed

NCT Number: NCT05864079

Developmental Endothelial Locus-1, Platelet Count, and Soluble P-selectin in Overweight and Obese Subjects

This observational study aims to detect serum levels of Developmental Endothelial Locus-1 (DEL-1), Platelet Count, and Soluble P-selectin (sP-sel) in Overweight and Obese Subjects. The main questions it aims to answer are:

* Is there a difference in serum DEl-1 levels in overweight and obese subjects compared to normal subjects? * Are there any relations between serum DEL-1 levels, sP-sel, and platelet count in overweight and obese subjects ?

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Key information

Conditions

Overweight and Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

Male

Study type

Observational

Primary location

Aswan University Hospital

Aswān, 81528, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male patients.
  • Age (18-65) years.
  • Healthy overweight and subjects.

Exclusion criteria

  • Patients with cardiovascular diseases.
  • Diabetic patients.
  • Previous history of thrombo-embolic diseases.
  • Patients with hyperthyroidism.
  • Patients with any type of malignancy.
  • Underlying hepatic or renal failure.
  • Major surgery within 60 days.

Treatment and study plan

Platelet count

Diagnostic Test

Platelet count in study groups

Developmental endothelial locus-1 (DEL-1)

Diagnostic Test

Serum DEL-1 in study groups

soluble P-selectin (sP-sel)

Diagnostic Test

Serum sP-sel in study groups

Primary outcomes

  1. Platelet count

    Time frame: 6 months

    platelet count in venous blood samples in normal-weight, overweight, and obese subjects

  2. Serum Developmental endothelial locus-1 levels

    Time frame: 6 months

    Serum developmental endothelial locus-1 in normal-weight, overweight, and obese subjects

  3. Serum Soluble P-selectin levels

    Time frame: 6 months

    Serum Soluble P-selectin in normal-weight, overweight, and obese subjects

Sponsors and collaborators

Lead sponsor

Aswan University Hospital

Other

Registry information

Official study title

Serum Levels of Developmental Endothelial Locus-1 and Its Relationship With Platelet Count and Soluble P-selectin in Overweight and Obese Subjects

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
May 18, 2023
Registry last updated
Jun 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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