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NCT Number: NCT06094218

Development of a Treatment Prognosis Calculator for the Prevention of Suicide

The goal of this interventional study is to develop and test a treatment prognosis calculator to identify which service members with suicidal ideation or behavior are likely to respond well to the current standard of care treatment and which should instead receive Brief Cognitive Behavioral Therapy (BCBT) as a first-line treatment.

The main aims of the study are:

* Aim 1: To develop a novel treatment prognostic calculator to predict response to treatment as usual (TAU) and identify treatment-seeking military personnel who are unlikely to respond adequately to TAU for the reduction of suicidal ideation. * Aim 2: To evaluate the performance of the treatment prognosis calculator in a new sample of treatment-seeking military personnel and determine whether BCBT is more effective than TAU for those patients who are predicted not to respond adequately to TAU.

Participants will receive mental health treatment as it is typically administered by their mental healthcare treatment team. Members of their mental healthcare treatment team may receive intensive training in BCBT. After their provider has received this training, they may use this treatment as part of standard of care treatment. The timing of this training will be determined randomly. Participants will complete self-report assessments at the beginning of the study (baseline) as well as 3, 6, 9 and 12 months after their participant begins. These assessments will include questions about feelings, thoughts, moods, impulses, substance use, and behavior.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Harding Hospital

Columbus, Ohio, 43210, United States

Location status: Recruiting

Location contact

Jay C. J. Fournier, PhD

CONTACT

[email protected]

6142939889

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • female and male active duty service members;
  • => 18 years old;
  • engaged in mental health treatment at one of the sites at study enrollment;
  • score >0 on the Columbia Suicide Severity Rating Scale (CSSRS) Screener-Recent, or indicated suicidal ideation on questions 4 or 5 of the Scale for Suicidal Ideation, indicating suicidal ideation within the last month;
  • able to understand and speak English;
  • able to provide consent.

Exclusion criteria

(1) participants with a psychiatric or medical condition that prevents them from providing informed consent or from participating in the treatments (e.g., psychosis, mania, acute intoxication).

Treatment and study plan

Brief Cognitive Behavioral Therapy (BCBT)

Behavioral

BCBT was developed to provide patients with the skills they need to better manage the cognitive, emotional, physiological, and behavioral components of acute suicidal crises.

Treatment as Usual (TAU)

Behavioral

Behavioral health treatment as it is typically provided at the treatment site.

Primary outcomes

  1. Suicidal Ideation

    Time frame: 6 Months

    Assess severity of suicidal ideation at 6 months with the Scale for Suicide Ideation (SSI)

Secondary outcomes

  1. Suicide Attempts

    Time frame: 12 Months

    Suicide attempts will be assessed with the Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R)

  2. Depression

    Time frame: 12 Months

    Depression will be assessed with the PROMIS-Depression Computer Adaptive Test (CAT)

  3. Hopelessness

    Time frame: 12 Months

    Hopelessness will be assessed with the abbreviated Beck Hopelessness Scale (BHS)

Study contacts

Contact information is provided by the study sponsor or research team.

Jay Fournier, PhD

CONTACT

[email protected]

614-293-9889

Sponsors and collaborators

Lead sponsor

Ohio State University

Other

Collaborators

  • United States Department of Defense

Registry information

Important dates

Study start
2023
Primary completion
2026
Study completion
2027
First posted
Oct 23, 2023
Registry last updated
Feb 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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