Mass General Cancer Center
Boston, Massachusetts, 02114, United States
Not Yet Recruiting
NCT Number: NCT07160933
Development of a Psychosocial Intervention to Reduce Post Traumatic Stress in Young Adult Survivors of Cancer
The goal of this study is to develop a virtual group intervention to address post-traumatic stress related to cancer in young adult cancer survivors (YACs, aged 18-39). The study team will do this by integrating evidence-guided treatments and expert clinician feedback (N=10) on the content, delivery, and structure of the intervention. Next, the study team will refine this intervention through a pilot trial with a group of YACs (N=80).
Not Yet Recruiting
Trial opening soon.
Get NotifiedKey information
Conditions
Age range
18 year–39 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
To be eligible for this study, participants will be:
- Currently aged between 18 - 39;
- Currently receiving or having completed treatment for cancer at the Mass General Cancer Institute within the past 5 years;
- Reporting a score denoting at least mild symptoms of PTSD on the Post-traumatic Stress Checklist 5 (PCL-5);
- English-speaking;
- Have access to a device with audio/video capabilities to complete virtual intervention sessions.
Exclusion criteria
- Unable to provide verbal consent
- Reporting active symptoms of psychosis that preclude safe participation.
Treatment and study plan
Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults
BehavioralA new group-based virtual intervention to address post-traumatic stress related to cancer in YACs, integrating evidence-guided treatments from Cognitive Processing Therapy and Mind-Body Resiliency interventions.
Primary outcomes
-
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
-
Intervention Feasibility: Proportion of Participants Completing the Program
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
-
Intervention Acceptability
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Study contacts
Contact information is provided by the study sponsor or research team.
Xinghan Zhu, B.S.
CONTACT
Zeba N Ahmad, Ph.D.
CONTACT
Sponsors and collaborators
Lead sponsor
Zeba Ahmad, Ph.D.
Other
Collaborators
- American Cancer Society, Inc.
Registry information
Official study title
Adaptation and Refinement of a Psychosocial Intervention to Reduce Post-Traumatic Stress in Young Adult Survivors of Cancer
Important dates
- Study start
- 2026
- Primary completion
- 2030
- Study completion
- 2030
- First posted
- Sep 8, 2025
- Registry last updated
- Mar 31, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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