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OpenTrials
Completed

NCT Number: NCT03192189

Development of a Decision-making Aid for Referring Severe Kidney Injury Patients for Nephrology Consultations

Acute kidney injury is a frequent and growing complication associated with a risk of progressing into a chronic kidney disease. Recent guidelines have recommended systematic consultations with a nephrologist 3-6 months following hospitalization. Risk factors of developing chronic kidney disease between hospital visits are understudied.

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Key information

Conditions

Chronic Kidney Diseases Acute Kidney Injury Chronic Disease Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Nimes

Nîmes, 30029, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >18 years
  • Suffering from acute kidney injury treated with dialysis
  • hospitalized in a university center from August 2016 to December 2017 with severe AKI defined according to 2 of the 3 criterion definitions of KDIGO stage AKI: an increase in SCr above 354 μmol/Lor renal replacement therapy (RRT) indication, but not the 3-fold increase in SCr increase within 7 days with SCr below 354 μmol/L.
  • The patient has been informed and does not oppose the study
  • The patient is insured or the beneficiary of a health insurance policy

Exclusion criteria

  • The patients is under judicial protection or state guardianship
  • Patient has chronic kidney disease(CKD) KDIGO stage 5
  • It proves impossible to give the patient clear information
  • patients living with kidney transplant
  • plan dialysis for bilateral surgery nephrectomy
  • patient refuse to participate and patients with no health insurance

Treatment and study plan

monitoring for progression to chronic kidney disease

Other

Collect clinical information and assess risk factors

Primary outcomes

  1. Develop a prognostic score of progression to chronic kidney disease at 6 months in patients requiring hospitalization for dialysis for acute kidney injury to identify those who would benefit from consultation with a nephrologist

    Time frame: 6 months

Secondary outcomes

  1. Identify new risk factors for progression to chronic kidney disease at 6 months post dialysis for acute kidney injury pre-hospitalization and during hospitalization and day of discharge

    Time frame: 6 months

  2. Identify renal phenotype of patients with chronic kidney disease

    Time frame: 6 months

    characterization from renal biopsy

  3. Evaluate mortality during hospital stay

    Time frame: 1 months

  4. Evaluate mortality at medium-term

    Time frame: 6 months

  5. Identify specific therapeutic interventions put into place during the 6 month consultation

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Acronym: IRA Cible

Important dates

Study start
2016
Primary completion
2017
Study completion
2018
First posted
Jun 20, 2017
Registry last updated
Nov 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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