Development of a Clinical Photographic Atlas for Skin Aging Based on the Characterization of Facial Dermal Collagen Using LC-OCT Technology

Single-center, single visit study in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria. The study is to develop a clinical photographic atlas to assess skin aging by studying the relationship between age, sun exposure and quantity of collagen measured non-invasively (LC-OCT). No product will be tested during the study.

Inclusion criteria

• Subject having signed an Informed Consent Form (ICF) before any trial related activity is carried out;
• Healthy female subject aged 20 to 75 years inclusive at the time of signing the ICF;
• Subject with a phototype I to III on Fitzpatrick's scale;
• Subject who is willing to follow the study procedures and to complete the study course;
• Subject registered with Social Security in agreement with French law on study research.

Exclusion criteria

• Male subject;
• Female subject who is pregnant or who is breast feeding;
• Subject with current participation in any other interventional clinical study, based on interview of the subject;
• Subject with facial dermatitis, rosacea, acne, eczema, psoriasis, skin rashes, open lesions, vitiligo or viral conditions such as herpes labialis;
• Subject who has collagen vascular disease, a significant systemic disease, immunological problems or inflammatory skin conditions on the face;
• Subject who has had a face lift;
• Subject has had a non-ablative and/or ablative laser procedure on the face in the past 3 months;
• Subject with a history of botulinum toxin or mesotherapy injections on the face within the last 6 months, or absorbable fillers injections (such as hyaluronic acid or autologous fat…) in the last 12 months or injectable implants (semi-permanent fillers) within the last 24 months;
• Subject having done a moderate to deep peeling or non-invasive rejuvenation techniques such as radiofrequency, ultrasound and lasers in the last 6 months;
• Subject having applied any cosmetic product (care cream, lotion, makeup) except usual cleansing products or any drug to her face on the day of the visit;
• Subject who has been deprived of their freedom by administrative or legal decision, or who is under care of a guardian or legal guardianship, or subject hospitalized in a medical or social establishment for any reason.