Translational Research Institute for Metabolism and Diabetes
Orlando, Florida, 32804, United States
Location status: Recruiting
Location contact
Heather Cornnell, PhD
PRINCIPAL_INVESTIGATOR
Recruitment Manager
CONTACT
Recruiting
NCT Number: NCT02663362
Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications
The purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
12 year–89 year
Sex eligibility
All sexes
Study type
Observational
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Male or female
- Age 12 - 89
- Healthy (self assessed)
- Weight under 350lbs
- Able to walk 50 yards without stopping
- Able to travel to hospital for study visits
- Able to follow a 3-step command
- Able to remain in Magnetic Resonance (MR) scanner for up to 2 hours
Exclusion criteria
- Have internal metal medical devices, including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws, metal fragments in your eye, or non-removable jewelry such as rings.
- Are unwilling or unable to complete the imaging procedures for the duration of the MRI scan due to claustrophobia or other reason.
- Serious mental illness that might preclude subject's ability to comply with study treatment
- Life expectancy of less than 1 year
- Are pregnant or plan on becoming pregnant in the next 8 weeks.
Treatment and study plan
To evaluate the reproducibility of acquiring multi-nuclear data on a new 3T Philips Magnet
OtherOutside standard MR instrumentation there will be no interventions.
Primary outcomes
-
Whole body fat quantification
Time frame: 1 hour
Secondary outcomes
-
Fat Microstructure
Time frame: 1 hour
A high resolution image of the structure of fat tissue.
Other outcomes
-
Flow high resolution imaging
Time frame: 1 hour
Image of the movement of fluids in the area being imaged.
-
Intramyocellular fat quantification
Time frame: 45 minutes
Use to determine the amount and types of fat inside muscle and liver.
-
Intrahepatic fat quantification
Time frame: 45 minutes
A measure of the amount of fat in the liver.
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
AdventHealth Translational Research Institute
Other
Registry information
Acronym: MRS VALIDATION
Important dates
- Study start
- 2012
- Primary completion
- 2026
- Study completion
- 2027
- First posted
- Jan 26, 2016
- Registry last updated
- Mar 30, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.