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OpenTrials
Active, Not Recruiting

NCT Number: NCT06358404

Developing a Peer Support Intervention for Depression in SCD

The purpose of this study is to assess the feasibility, acceptability, and fidelity of an 8-week intervention where peer coaches will deliver depression care to adults 60 years of age or older who have depression and subjective cognitive decline.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

About this study

With support from the MADRC ORE Core, we will recruit 30 community-dwelling older adults to conduct an open pilot study of PeersCOG. Trained and supervised peer coaches will deliver depression care to adults 60 years of age and older with depression and subjective cognitive decline in an 8-week intervention using video chats and texts. We will use mixed methods to assess feasibility, acceptability, and fidelity. We will use validated instruments to assess the preliminary outcomes, including depression, SCD, functioning, and social factors at baseline, 8 weeks, and 3 months, and we will conduct post-intervention interviews with stakeholders at 8 weeks. Older adult participants will be asked to name a study partner who will support the older adult throughout the study in terms of study enrollment. They may also have additional perspectives on the impact of impaired cognition and depression on daily living and related needs. The older adult will not be excluded if the study partner is not available.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Older adults aged 60+
  • Endorse subjective cognitive decline
  • Endorse depressive symptoms
  • not currently experiencing suicidal ideation nor active, untreated manic, psychotic, or substance use disorder
  • fluent in English and able to give informed consent

Exclusion criteria

  • Meets diagnostic criteria for mild cognitive impairment or Alzheimer's dementia
  • Meets diagnostic criteria for a current major depressive disorder
  • have a history of neurological and psychiatric comorbidities such as major depressive disorder in the past 12 months

Treatment and study plan

PeersCOG

Behavioral

. The intervention will consist of 8 weekly video chats focused on emotional, appraisal, and informational support delivered by community-based older adult peer coaches to adults 60 years of age and older with subthreshold depression and SCD.

Primary outcomes

  1. Feasibility of Intervention

    Time frame: Measured at baseline enrollment

    Level of participant engagement: how many screened older adults agree to participate in the intervention and complete baseline assessments

  2. Acceptability of Intervention

    Time frame: Measured during intervention (8 weeks)

    Number of meetings older adults complete with peer coach

  3. Fidelity of Intervention

    Time frame: Measured during intervention (8 weeks)

    Degree of adherence to intervention

Sponsors and collaborators

Lead sponsor

Massachusetts General Hospital

Other

Collaborators

  • National Institutes of Health (NIH)

Registry information

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Apr 10, 2024
Registry last updated
Jul 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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