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Recruiting

NCT Number: NCT05830903

Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques

Establish a novel vocational training program and test its validity in a pilot study.

Recruiting

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Key information

Conditions

Schizophrenia Cognition Disorders Cognitive Dysfunction Cognitive Impairment Mental Disorders Neurocognitive Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University Hospital

Taipei, Taiwan

Location status: Recruiting

Location contact

Yi Ling Chien, M.D., Ph.D.

CONTACT

[email protected]

886-2-2312-3456 ext. 66013

About this study

40 schizophrenia patients will be recruited to join the virtual reality based vocational training program, the training effect will be compared by interview skills and problem solving before and after the training.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having a diagnosis of schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders -5th version
  • Aged between 20 and 55 years.
  • Motivated to have a job.
  • Having a full-scale IQ > 70 on the Wechsler Adult Intelligence Scale-version IV.
  • Having a PANSS positive scale < 70, indicating a stable condition during the illness course.

Exclusion criteria

  • Comorbid with other major psychiatric disorders (i.e., bipolar disorders) or neurological diseases.
  • Substance abuse within one year.
  • Visual impairment and/or hearing impairment that would preclude participation in the VR-based training program.

Treatment and study plan

VR-assisted occupational training

Behavioral

VR-assisted occupational training

Primary outcomes

  1. clinical ratings of schizophrenia symptoms

    Time frame: 8 weeks

    The Positive and Negative Syndrome Scale (PANSS) is a 30-item rating scale completed by trained research staff. Scores for positive, negative, cognitive disorganization, emotional discomfort, and hostility/excitement symptoms were derived from factor-derived scoring published.

    • There are 30 different symptoms rated from 1 to 7 (total score of 210). Higher the score, worse the symptoms

  2. vocational skills

    Time frame: 8 weeks

    Job interview role-play performance will be scored across nine domains: conveying oneself as a hard worker, sounding easy to work with, conveying that one behaves professionally, negotiation skills (requesting one day off), sharing things in a positive way, sounding honest, sounding interested in the position, comfort level, and establishing rapport

  3. global improvement

    Time frame: 8 weeks

    Clinical Global Impression Improvement scale (CGI-I) rating scales are commonly used measures of symptom severity, treatment response and the efficacy in treatment studies of patients with mental disorders. It is a 7-point scale that require clinician to assess how much the patient's illness has improved or worsened relative to baseline. "1" meaning very much improved, "7" meaning very much worsen.

Study contacts

Contact information is provided by the study sponsor or research team.

Yi Ling Chien

CONTACT

[email protected]

886-2-2312-3456 ext. 66013

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Important dates

Study start
2020
Primary completion
2026
Study completion
2026
First posted
Apr 26, 2023
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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