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Completed

NCT Number: NCT03075332

Detraining in People Living With HIV/AIDS

The goal of this study was to evaluate the effect of detraining in the components of physical aptitude of people living with HIV/Aids (PVHA).

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Key information

Conditions

Lipodystrophy Syndrome, HIV Atrophy Blood-Borne Infections Communicable Diseases Genital Diseases HIV Infections HIV-Associated Lipodystrophy Syndrome Immune System Diseases Immunologic Deficiency Syndromes Infections Lentivirus Infections Lipid Metabolism Disorders Lipodystrophy Metabolic Diseases Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Nutritional and Metabolic Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms RNA Virus Infections Retroviridae Infections Sarcopenia Sexually Transmitted Diseases Sexually Transmitted Diseases, Viral Signs and Symptoms Skin Diseases Skin Diseases, Metabolic Skin and Connective Tissue Diseases Urogenital Diseases Virus Diseases

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Juliany de Souza Araujo, Natal, Rio Grande do Norte, Brazil

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About this study

The study was experimental with a sample composed by an Experimental Group (EG) with 11 PVHA, under antiretroviral therapy and a Control Group (CG) with 10 individuals without the infection; all which were under medical release and insufficiently active. The body composition was evaluated through the DXA, as well as the cardiorespiratory aptitude through the ergometer and the strength of the upper and lower limbs through dynamometry. Both groups conducted interventions with concurrent training for 15 weeks and the interruption of exercise was evaluated after a period of 5 weeks.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Group experience to have a diagnosis of at least 2 years living with HIV / AIDS being in clinical follow-up in the Specialized Attention Services in HIV / AIDS (SAE), using ART, TCD4 lymphocyte count equal to or greater than 500 copies / mm³, viral load Undetectable (≤ 50 copies / mm³)
  • Group control without any diagnosis of HIV / AIDS or any other pathology. Both groups completed the exercise program with a minimum frequency of 75%.

Exclusion criteria

  • Both groups taking part in any physical exercise in time of detraining

Treatment and study plan

combined training

Other

Combined training consisting of aerobic and resisted training in the same training session for 15 weeks followed by 5 weeks of detraining

Primary outcomes

  1. Capacity cardiorespiratory

    Time frame: 21 weeks

    ml (cardiorespiratory aptitude through the ergometer)

Secondary outcomes

  1. test force

    Time frame: 21 weeks

    kg (strength of the upper and lower limbs through dynamometry)

Other outcomes

  1. body composition

    Time frame: 21 weeks

    kg (body composition was evaluated through the DXA)

Sponsors and collaborators

Lead sponsor

Universidade Federal do Rio Grande do Norte

Other

Registry information

Official study title

Detraining in the Components of Physical Aptitude in People Living With HIV/ AIDS

Acronym: PVHA

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Mar 9, 2017
Registry last updated
Mar 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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