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OpenTrials
Completed

NCT Number: NCT00911703

Determining When Patients Hospitalized With Acute Heart Failure Can Be Safely Sent Home (The DECIDE Study)

The purpose of this study is to determine if certain findings (blood tests, symptom improvement, etc.) after acute heart failure treatment can identify a group of patients who are safe for early hospital discharge.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Cincinnati, Cincinnati, Ohio, United States

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About this study

A fundamental question faced by physicians treating acute decompensated heart failure (ADHF) is "When has treatment worked sufficiently for safe discharge, and who requires further treatment?" Patients with ADHF have a high incidence of morbidity and mortality. Current guidelines for emergency department (ED) and hospital disposition of patients with ADHF are based on limited empirical evidence. This creates clinical uncertainty regarding disposition leads to prolonged hospitalizations, higher costs and increased resource consumption. The specific aim of the study is to develop a prediction rule from readily available clinical data to help physicians identify ADHF patients eligible for safe and early discharge from the ED and hospital after treatment is initiated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fulfill the modified Framingham criteria
  • Have baseline data available within 1 hour of initial ED therapy
  • Have previously documented systolic dysfunction (ejection fraction less than 50%) by echocardiogram
  • Willing and able to give informed consent

The exclusion criteria are:

  • Patients less than 18 years of age.

Treatment and study plan

Primary outcomes

  1. Heart-failure related adverse events

    Time frame: Measured 5 days and 30 days after ED presentation

Sponsors and collaborators

Lead sponsor

Vanderbilt University

Other

Collaborators

  • Abbott Point of Care
  • Inovise Medical
  • National Heart, Lung, and Blood Institute (NHLBI)

Registry information

Official study title

Treatment Endpoints in Acute Decompensated Heart Failure

Acronym: DECIDE

Important dates

Study start
2008
Primary completion
2014
Study completion
2015
First posted
Jun 2, 2009
Registry last updated
Apr 29, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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