Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07550231

Determining the Optimal Dose of AD-211 in Patients With Osteoarthritis of the Knee

The purpose of this study is to determine the optimal dose of AD-211 in patients with osteoarthritis of the knee.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Osteoarthritis of the Knees

Age range

19 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

About this study

Osteoarthritis of the knee

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Signed informed consent
  • Patients with osteoarthritis of the Knee
  • Other inclusions applied

Exclusion criteria

  • Patients with secondary osteoarthritis of the knee
  • Other exclusions applied

Treatment and study plan

AD-211-L

Drug

Per oral, 1 tablet twice daily during the treatment period.

AD-211-M

Drug

Per oral, 1 tablet twice daily during the treatment period.

AD-211-H

Drug

Per oral, 1 tablet twice daily during the treatment period.

AD-2113

Drug

Per oral, 1 tablet twice daily during the treatment period.

Placebo to AD-211-L/M

Drug

Per oral, 1 tablet twice daily during the treatment period.

Placebo to AD-211-H

Drug

Per oral, 1 tablet twice daily during the treatment period.

Placebo to AD-2113

Drug

Per oral, 1 tablet twice daily during the treatment period.

Primary outcomes

  1. Change from baseline in 100 mm Pain VAS score during activity over the past 24 hours in the target knee

    Time frame: Baseline to Week13

Study contacts

Contact information is provided by the study sponsor or research team.

Hyeji Lee

CONTACT

[email protected]

+82318915604

Sponsors and collaborators

Lead sponsor

Addpharma Inc.

Industry

Registry information

Official study title

A Randomized, Double-Blind, Parallel, Multi-Center, Phase 2 Clinical Trial to Determine the Optimal Dose of AD-211 in Patients With Osteoarthritis of the Knee

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 24, 2026
Registry last updated
Apr 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.