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Recruiting

NCT Number: NCT05914987

Determining Individualized Cancer Therapy in Pancreatic Cancer

This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Froedtert Hospital and the Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

Location status: Recruiting

Location contact

Mandana Kamgar, MD

CONTACT

[email protected]

414-805-8900

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years.
  • Pathologically confirmed pancreatic cancer.
  • Ability to understand a written informed consent document and the willingness to sign it

Exclusion criteria

  • Age <18 years.
  • Primary cancer diagnosis other than pancreatic cancer.

Treatment and study plan

Targeted Therapy

Other

Approved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.

Primary outcomes

  1. Number of Subjects Receiving Targeted Therapy

    Time frame: 5 years

    This measure is the number of study subject's whose treating physician prescribes and subsequently receives the therapeutic recommendation of the Molecular Tumor Board.

Study contacts

Contact information is provided by the study sponsor or research team.

Cancer Center Clinical Trials Office

CONTACT

[email protected]

1-414-805-8900

Sponsors and collaborators

Lead sponsor

Medical College of Wisconsin

Other

Registry information

Official study title

Profile-Related Evidence Determining Individualized Cancer Therapy in Pancreatic Cancer (PREDICT-PANC)

Acronym: PREDICT-PANC

Important dates

Study start
2023
Primary completion
2028
Study completion
2033
First posted
Jun 22, 2023
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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