Skip to main content
OpenTrials
Completed

NCT Number: NCT00717912

Determination of the Glycemic Index and the Insulinemic Index of a Sweetener Syrup

The purpose of the study is to determine the glycemic index and the insulinemic index of a sweetener syrup

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Volunteers

Age range

18 year–50 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Biofortis

Nantes, 44200, France

About this study

Glycemic index is a measure of how carbohydrate-containing foods affect blood glucose levels. All foods that contain carbohydrates, such as starchy vegetables (potatoes, corn), desserts, fruits, bread, pasta, and rice, can be tested for how they affect blood sugar levels after being eaten. Glycemic index is assessed by having one or more people eat a specific amount of a single food (usually 50 grams of digestible carbohydrate) and then measuring the change in blood sugar levels compared with the levels achieved after they have eaten a control food containing the same amount of digestible carbohydrate, such as white bread or glucose. The average change in blood sugar levels over a set period of time relative to the levels after consumption of the control food, usually white bread or glucose, is the food's glycemic index.

Insulinemic index is measure with the same methodology.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 18-50 years
  • male
  • healthy volunteers
  • BMI above 25 kg/m²

Exclusion criteria

  • no medical history of hypercholesterolemia, high pressure blood, diabetes, sugar intolerance
  • food allergy
  • kidney deficiency
  • liver troubles
  • gastro-intestinal troubles
  • drugs which impair sugar and lipid metabolism

Treatment and study plan

Experimental sweetener syrup

Other

3 glucose and insulin responses with experimental sweetener syrup : 50 grams of digestible carbohydrate plus fiber

Classical sweetener syrup

Other

1 glucose and insulin responses with classical sweetener syrup : 50 grams of digestible carbohydrate plus fiber

Classical sugar syrup

Other

3 glucose and insulin responses with classical sugar syrup : 50 grams of digestible carbohydrate plus fiber

Primary outcomes

  1. Glycemic Index

    Time frame: Every 48 hours (each new intervention), over a 2 hour blood glucose challenge

    The specific measure that will be use to determine the glycemic responses is the change in blood sugar levels compared with the levels achieved after they have eaten a control food containing the same amount of digestible carbohydrate.

    Sugar syrup was used as the reference food, giving it a glycemic index value of 100 by definition. The AUC of the test food is divided by the AUC of the standard (glucose) and multiplied by 100. Low GI: 55 or less, Medium GI: 56-69, High GI: 70 and above

Secondary outcomes

  1. Insulinemic Index

    Time frame: Every 48 hours (each new intervention), over a 2 hour blood glucose challenge

    The specific measure that will be use to determine the insulinemic responses is the change in blood insuline levels compared with the levels achieved after they have eaten a control food containing the same amount of digestible carbohydrate.

    Sugar syrup was used as the reference food, giving it a insulinemic index value of 100 by definition. The AUC of the test food is divided by the AUC of the standard (glucose) and multiplied by 100. Low GI: 55 or less, Medium GI: 56-69, High GI: 70 and above

Sponsors and collaborators

Lead sponsor

Routin SA

Industry

Registry information

Official study title

Determination of the Glycemic Index and the Insulinemic Index of a Sweetener

Important dates

Study start
2008
Primary completion
2008
Study completion
2008
First posted
Jul 18, 2008
Registry last updated
Jul 13, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.