CHR Metz-Thionville/Hopital de Mercy
Metz, 57085, France
Location status: Recruiting
Location contact
Arpiné EL NAR, PhD
CONTACT
Marc ENGELS-DEUTSCH, MD
PRINCIPAL_INVESTIGATOR
Paul RETIF, MD
SUB_INVESTIGATOR
CONTACT
NCT Number: NCT05888935
Dental periapical damages can have various reasons and is reflected by a radiolucent lesion on complementary imaging: angulated retro-alveolar (RA) radiographs, dental panoramic radiographs, and three-dimensional imaging such as computed tomography (CT) or cone-beam computed tomography (CBCT).
For the radiographic detection of these deep periodontal lesions, the dental panoramic represents a first approach commonly performed with relatively low radiation. The investigation can be followed by retroalveolar radiology imaging that are more localized and more precise. However, using these techniques, the detection rates of these lesions are low (20% and 36% respectively), it is necessary to use three-dimensional tomographic investigation to be more discriminating (69%). The gold standard imaging for detection of these lesions is CBCT followed by retroalveolar radiography (~2x less sensitive than CBCT) and panoramic radiography (~2x less sensitive than RA). Although not a full-thickness radiograph, the dental panoramic has the advantage of being more commonly performed while being less radiating than CBCT and giving a global view of the dental arches on a single image.
The detection of periapical lesions is done after a clinical assessment and a visual appreciation of the complementary examinations.
The aim of this project is to improve the detection of periapical lesions, by developing an algorithm able to identify them on a panoramic dental radiograph. This algorithm is based on a deep learning system trained with reference data including panoramic dental imaging and CBCT with an acquisition interval of less than 3 months. The model is based on a previous work, will improve the quality of the initial data (using CBCT), using innovative artificial intelligence algorithms (transfer learning).
Interested in participating?
Request Info18 year and older
All sexes
Observational
Metz, 57085, France
Location status: Recruiting
Arpiné EL NAR, PhD
CONTACT
Marc ENGELS-DEUTSCH, MD
PRINCIPAL_INVESTIGATOR
Paul RETIF, MD
SUB_INVESTIGATOR
CONTACT
The final objective of the research is to improve the early diagnosis of periapical lesions, which would allow a better and faster care of these lesions namely at early stages. This represents a major public health interest since these lesions can be responsible for multiple local and regional pathologies (osteomyelitis, cervico-facial cellulitis, thrombophlebitis, cerebral abscesses...) or even more serious general pathologies (cardiac pathologies, cardiovascular diseases, diabetes, renal diseases, tendinopathies...). For certain target groups such as the military and high-level athletes, this research would make it possible to improve the assessment carried out before medical aptitude or club transfer.
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 2 years
measurement of the F1 score. The F1 score is calculated as the harmonic mean of the precision and recall scores.
It ranges from 0-100%, and a higher F1 score denotes a better quality classifier.
Time frame: 2 years
measurement of the true positives, true negatives, false positives, false negatives
Contact information is provided by the study sponsor or research team.
Centre Hospitalier Régional Metz-Thionville
Other
Detection of Periapical Lesions on Dental Panoramic Images Based on Artificial Intelligence Using Cone Beam Computed Tomography
Acronym: OPTITOMO
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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