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NCT Number: NCT05968053

Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)

Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids.

Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients.

The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.

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Key information

Conditions

Carotid Artery Stenosis Aneurysm Arterial Occlusive Diseases Brain Diseases Brain Neoplasms Brain Tumor Cardiovascular Diseases Carotid Artery Diseases Carotid Stenosis Central Nervous System Diseases Central Nervous System Neoplasms Cerebrovascular Disorders Glioma Hemorrhage Intracranial Aneurysm Intracranial Arterial Diseases Intracranial Hemorrhages Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue Neoplasms, Neuroepithelial Nervous System Diseases Nervous System Neoplasms Neuroectodermal Tumors Pathologic Processes Pathological Conditions, Signs and Symptoms Vascular Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, 100070, China

Location status: Recruiting

Location contact

Fa Lin, MD

CONTACT

[email protected]

13681107240

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-80 years
  • Any type of neurosurgery

Exclusion criteria

·refusal of the patient to participate

Treatment and study plan

biological samples analysis

Diagnostic Test

biological samples analysis

Primary outcomes

  1. microplastics

    Time frame: baseline, intraoperative

    Detection of microplastics in human brain tissue and the blood undergoing neurosurgery

  2. nanoplastics

    Time frame: baseline, intraoperative

    Detection of nanoplastics in human brain tissue and the blood undergoing neurosurgery

Study contacts

Contact information is provided by the study sponsor or research team.

Fa Lin, MD

CONTACT

[email protected]

13681107240

Xiaolin Chen, MD

CONTACT

[email protected]

13810624845

Sponsors and collaborators

Lead sponsor

Beijing Tiantan Hospital

Other

Registry information

Official study title

Presence of Microplastics and Nanoplastics in Neurosurgery Patients

Acronym: DT-MiNi

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Aug 1, 2023
Registry last updated
Jan 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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