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NCT Number: NCT06193356

Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable

Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may propagate into post-colonoscopy colorectal cancer. Expert series suggest scar recognition and interrogation is well performed with a high negative predictive value of endoscopic imaging vs histopathology. In this study the authors will investigate the performance of endoscopic imaging in detecting RRA at an endoscopic resection scar amongst general endoscopist and the impact of a learning intervention on recognition of RRA.

After consent is given, the participant will open the online survey and fill this in.

First the participant will be asked to create a pseudonym (name+year of birth) and fill in their demographical information (Grade, years in current role, colonoscopy experience, experience of colonic tissue resection, country of employment

The first 15 pictures will be shown prior to a learning intervention. For each picture the same questions will be asked:

* Is this an endoscopic resection scar? * Based on this image does the scar demonstrate evidence of residual or recurrent adenoma (RRA)? * What is your level of confidence? * If the scar shows RRA, how would you treat it? (skip if you feel no RRA). * If the scar does not show RRA do you feel there is another diagnosis? After the first 15 pictures a video-based learning tool will be shown on detection of RRA.

After the learning tool 15 different pictures will be shown, the same questions will be asked. All responses will be collected by the investigators. Statistical analysis will be performed using visual studio code (Microsoft, Redmond, USA) Images will be selected from the 'Australian Colonic LSL Endoscopic Resection Study' (ACE) database, which is an international multicentre registry of images and videos for retrospective analysis of colonic lesions. Images, videos, procedural information, and histopathological data are stored on a secure online web portal after written informed consent of every participating patient.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UZ Gent

Ghent, 9000, Belgium

Location status: Recruiting

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Endoscopists of any experience level

Exclusion criteria

  • non consenting adults

Treatment and study plan

Learning tool

Other

Video based learning tool about detection of endoscopic resection scars and recurrence.

Primary outcomes

  1. Performance of detecting a recurrence at an endoscopic resection scar.

    Time frame: 2 years

    Performance of detecting a recurrence at an endoscopic resection scar.

Secondary outcomes

  1. Performance of a learning tool in improving detection of recurrence at an endoscopic resection scar

    Time frame: 2 year

    Performance of a learning tool in improving detection of recurrence at an endoscopic resection scar

  2. Difference in performance of detecting a recurrence at an endoscopic resection scar between endoscopists with different experience level

    Time frame: 2 year

    Difference in performance of detecting a recurrence at an endoscopic resection scar between endoscopists with different experience level

  3. Performance of a learning tool in improving detection of recurrence at an endoscopic resection scar compared between endoscopists with different experience level

    Time frame: 2 year

    Performance of a learning tool in improving detection of recurrence at an endoscopic resection scar compared between endoscopists with different experience level

Study contacts

Contact information is provided by the study sponsor or research team.

David J trate, PhD

CONTACT

[email protected]

09 332 21 11 ext. +32

Sander Smeets, MD

CONTACT

[email protected]

09 332 21 11 ext. +32

Sponsors and collaborators

Lead sponsor

University Hospital, Ghent

Other

Registry information

Official study title

Detection of Endoscopic Resection Scars and Delineation of Recurrence Amongst Non-experts is Less Accurate Than Experts But Trainable in a Short Learning Intervention

Acronym: SCAR

Important dates

Study start
2024
Primary completion
2026
Study completion
2027
First posted
Jan 5, 2024
Registry last updated
Nov 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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