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OpenTrials
Active, Not Recruiting

NCT Number: NCT03457935

Detection of Early Idiopathic Pulmonary Fibrosis

The purpose of the study is to determine if miR200 family may serve as a biomarker of IPF.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Idiopathic Pulmonary Fibrosis Lung Diseases Lung Diseases, Interstitial Pulmonary Fibrosis Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Temple University

Philadelphia, Pennsylvania, 19140, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for IPF Patients:

  • Informed consent
  • Subjects ≥ 40 y.o.
  • Naive patients with no IPF treatment
  • IPF diagnosis based on the ATS/ERS/JRS/ALAT criteria

Inclusion criteria

for non-IPF ILD Patients:

  • Informed consent
  • Subjects ≥ 18 y.o.
  • ILD diagnosis

Exclusion criteria

  • HIV
  • Hepatitis B
  • Hepatitis C
  • Pregnant or lactating women

Inclusion criteria

for controls: informed consent >18 years old; no lung diseases

Treatment and study plan

Blood Samples

Other

Blood samples

Primary outcomes

  1. To determine miR200 levels (fold change) in blood samples.

    Time frame: Baseline (one time).

    MicroRNAs (miRs) are noncoding small RNAs, which regulate numerous physiological and pathological processes. miR200 levels will be measured in blood samples collected from control subjects, non-IPF ILD and IPF patients. These samples will be used for identifying biomarkers for IPF.

Sponsors and collaborators

Lead sponsor

Temple University

Other

Collaborators

  • Boehringer Ingelheim

Registry information

Official study title

The Role of the miR200 Family in the Restoration of Normal Lung Homeostasis and Detection of Early IPF

Important dates

Study start
2018
Primary completion
2025
Study completion
2026
First posted
Mar 8, 2018
Registry last updated
Dec 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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