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Completed

NCT Number: NCT02423135

Detection of Autologous DEHP (DiEthylHexyl Phthalate)-Free Blood Transfusion in Anti-doping

The aim of the proposed project is to perform a clinical study in which volunteers will receive autologous blood transfusions in DEHP-free blood bags.

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Key information

Conditions

Transfusion Reaction Hematologic Diseases Hemic and Lymphatic Diseases Immune System Diseases

Age range

20 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Swiss Laboratory for Doping Analyses

Épalinges, Canton of Vaud, 1066, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Have to fill the swiss blood donation formulary

Exclusion criteria

  • Anemia
  • Cardiovascular disease
  • Neurologic disease
  • Not performed a blood donation for 5 weeks ago the start of the study.
  • Immunological disease

Treatment and study plan

Autologous blood transfusion

Biological

Volunteers make a blood donation and after 36 days of storage this blood is re-infused in the same volunteers.

Primary outcomes

  1. Measurement of blood parameters profile, iron metabolism and genomic compounds

    Time frame: 1 month

    Blood profiling such as measurement of concentration of different blood cells and hemoglobin will be measured up to 15 days after blood-reinfusion. Concentration of free-iron, ferritin and hepcidin will be measured in plasma and serum up to 15 days after blood re-infusion.

    Concentration of circulating microRNAs will be measured in plasma also up to 15 days after blood re-infusion. All measures are compared.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Vaudois

Other

Registry information

Official study title

Detection of Autologous DEHP (DiEthylHexyl Phthalate)-Free Blood Transfusion Using a Combination of Multiple Biomarkers in Different Matrices.

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Apr 22, 2015
Registry last updated
Apr 22, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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