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Completed

NCT Number: NCT01436799

Desflurane Versus Propofol in the Sitting Position

The investigators hypothesized that both propofol and desflurane would decrease the regional oxygen saturation (rSO2) but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position.

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Key information

Conditions

Cerebral Ischemia Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The investigators hypothesized that both propofol and desflurane would decrease the rSO2 but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position. Therefore, the purpose of this study was to investigate the effect of desflurane and propofol on rSO2 values during the beach chair position for shoulder arthroscopy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Forty patients,
  • ASA class I or II,
  • undergoing shoulder arthroscopy

Exclusion criteria

  • Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index > 30) were excluded from this study.

Treatment and study plan

Propofol

Drug

anaesthesia was induced with the effect-site concentration of propofol 5.0 μg ml-1 mainly.

Desflurane

Drug

anaesthesia was maintained by desflurane 4-7vol%

Other names: Des

alfentanil

Drug

administration of alfentanil 10 μg kg-1 for anesthetic induction

Other names: alf

Rocuronium

Drug

administration of rocuronium 0.6 mg kg-1 for anesthetic induction

Other names: roc

Primary outcomes

  1. Regional Cerebral Oxygen Satuation (rSO2)

    Time frame: 1, 3, 5, 7, and 9 min after the beach chair position

    definitive values of regional cerebral oxygen saturation(rSO2,%) values are described as mean (SD)

Sponsors and collaborators

Lead sponsor

Gachon University Gil Medical Center

Other

Registry information

Official study title

International Review Board of Gachon University Gil Hospital

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Sep 20, 2011
Registry last updated
Sep 9, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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