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Completed

NCT Number: NCT02075424

Descriptive Study of Biological Stress and Perceived Stress at the Center 15

The purpose of this study is to describe biological stress (cortisolemia) and perceived stress in Emergency Call Center Operators and Doctors while processing a center 15 call.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre Hospitalier Régional Metz Thionville

Metz, 57085, France

About this study

Sample description : qualitative variables be expressed as percentages, numbers and 95% confidence intervals Quantitative variables will be expressed as means, standard deviations or medians, range, interquartile intervals Description of biological stress : it will be described by calculating the difference between the observed peek or peeks of cortisol ans the cortisol level measured at rest (means, standard deviations or medians, range, interquartile intervals) Description of perceived stress : the AVS will be described in terms of means and standard deviation Comparison of the peek-delta/base level of cortisol in the 3 different workstations of the call center operators according to the non parametrical Kruskall Wallis test. Same for the lengthof service of the call operator, the severity of the call and the status of the doctor The AVS score (perceived stress) will be compared to the peek-delta/base level of cortisol (biological stress) thanks to the Spearmann correlation coefficient.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • medical and paramedical staff from the center 15 (call operators, emergency doctors and general practitioners)
  • healthy volunteers having received the specific information letter regarding the sudy and having signed the clarified consent form
  • healthy volunteers are affiliated to the french social welfare

Exclusion criteria

  • chronic alcoholism
  • women under oestroprogestative hormonal treatment
  • high level athletes
  • healthy volunteers under steroids treatment
  • healthy volunteers suffering from a mental health related disorder
  • fever on the day the sample is taken
  • healthy volunteers with endocrine disorders

Treatment and study plan

salivary sampling by a biomnis swab

Other

Each call operator will have a series of salivary sampling taken when assigned to call reception, to the unit deployment station and to the assessment station.

Only one sampling will occur to doctors who are assigned to a single workstation.

Sampling will be taken every 15 minutes during one hour and half and one last sample will be taken 2 hours after the call.

To improve interpretation of the results, a series of control-samples will be taken among the call operators and doctors during a day off and not during a security break.

There will be 4x8 samples taken for each call operator and 2x8 samples per doctor.

They will also be frozen at a temperature of -4°C and sent to the laboratory of the CHR Metz Thionville.

Primary outcomes

  1. biological stress by salivary cortisol secretion

    Time frame: every 15 minutes after the emergency call and during 2 hours

Secondary outcomes

  1. perceived stress : VAS and SPPN questionnaire

    Time frame: VAS is assessed four times (once after each emergency call) during the first salivary sampling. SPPN once, on day 1, remote the emergency call (within the hourspreceding or following the emergency call)

    SPPN : Negative and Positive Professional Stress, before the first salivary sampling.

    VAS : Visual Analogic Scale,

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Régional Metz-Thionville

Other

Registry information

Official study title

Descriptive Study of Biological Stress and Perceived Stress in Call Regulation Operators and Doctors When Processing a Call at the Center 15

Acronym: RegulStress

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Mar 3, 2014
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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